Barcelona fired coach Ernesto Valverde and replaced him with former Real Betis coach Quique Setien.
The 55-year-old Valverde helped the club to two consecutive La Liga titles and led this season due to the goal difference.
However, the Catalan team has shown a number of unconvincing performances under his leadership and has not reached the Champions League final.
The 61-year-old Setien led Betis to his highest goal since 2005 and the semi-finals of the Copa del Rey before he left in May.
He has agreed to a two and a half year contract and will be presented to the media on Tuesday at 1:30 p.m. GMT
In a statement, Barca said they had an agreement with Valverde to terminate his contract and thanked him "for his professionalism, dedication, commitment, and always positive attitude toward everything that makes the Barca family special."
Setiens success at Betis
Valverde was under pressure towards the end of last season after Liverpool lost 0-3 in the Champions League semi-final after the first leg and the Copa del Rey against Valencia.
The defeat against the Reds was particularly bad because it reminded them of the Roma collapse last season and suggested that he hadn't corrected weaknesses in his team.
Valverde led the Catalans to the top of the table halfway through the season, but the fluid representations fans have grown accustomed to over the past 15 years have been sporadic.
Their away form was particularly disappointing with defeats at Athletic Bilbao, Granada and Levante and a draw at Osasuna, Real Sociedad and Espanyol.
Setien comes to the Nou Camp as a highly regarded trainer.
After managing the lower leagues, he led Las Palmas to 11th place in the La Liga – the best result in 40 years – and continued his success at Betis. In his first season, he finished sixth and qualified for the Europa League.
Betis also secured victories against Barca, Real Madrid and Atletico Madrid in his two-year term. He left the Seville outfit by mutual agreement in the summer.
Former Barcelona midfielder Xavi was closely associated with the role of head coach. He confirmed media reports that he had spoken to the club's sports director, Eric Abidal, and manager, Oscar Grau, over the weekend before declining the club's offer.,
Other names are said to have been associated with the association These included former Tottenham manager Mauricio Pochettino, who managed rival Espanyol, and current B-team manager Xavi Garcia Pimienta.
"Setien is a pious student of Cruyffian football" analysis
Spanish football expert Andy West
The most surprising thing about Ernesto Valverde, who was fired from Barcelona, is that it took so long.
Since that devastating night in Anfield in May, Valverde has never had a chance to reverse the team's rather aimless path.
Now this task falls to the former manager of Las Palmas and Real Betis, Quique Setien, who will fervently focus on restoring the team's famous, fast-paced, haunting and concise passport style, which had slowly been undermined by the more pragmatic Valverde.
Setien – whose stubborn character makes him a divisive figure across Spain – is a devout supporter of Cruyffian football, and from now on it is certain that Barca will play "Barca" football again.
But whether they can play it well is another question – the aging legs of Lionel Messi, Sergio Busquets, Gerard Pique and Jordi Alba may struggle to maintain the physical intensity required to make this approach successful, and that The coming months will be a fascinating test of whether an open-minded football philosophy can still deliver results.