Premier League leader Liverpool took the lead with a 1-0 win at Tottenham by 16 points, while Manchester United beat Norwich at Old Trafford.
Roberto Firmino scored the only goal at Tottenham Hotspur Stadium at the end of the first half, but Spurs should have equalized when Giovani Lo Celso made a cross pass just a few yards from goal. Jürgen Klopp's Reds have now got 61 points from 21 games – a record for this stage of a season in one of the five best leagues in Europe.
Marcus Rashford scored two goals in his 200th appearance for Manchester United how they beat Norwich 4-0.
Rashford clung to Juan Mata's cross to open the lead at Old Trafford before doubling the lead after the break from the penalty spot after Brandon Williams was overthrown by Norwich goalkeeper Tim Krul.
Anthony Martial headed the third goal just three minutes later, before Mason Greenwood won the victory after replacing him as a substitute.
Chelsea sent Burnley Jorginho's penalty led to a 3-0 win.
The Italian midfielder met coolly after Willian was overthrown by Matt Lowton before Tammy Abraham scored the blues' second goal with a header shot by Nick Pope.
Callum Hudson-Odoi scored third for Chelsea with his first Premier League goal.
Ranked next Leicester fell through a surprising defeat SouthamptonDanny Ings scored a 2-1 win for the Saints.
Dennis Praet shot a cross from birthday boy Jamie Vardy to score his first goal for Leicester before Stuart Armstrong equalized for Southampton just five minutes later.
Ings scored the winning goal after Che Adams shot on goal after an offside shot by Kasper Schmeichel while Jonny Evans of the video assistant referee (VAR) rejected a late goal.
Jordan Ayew's deflected equalizer on Saturday afternoon brought in a point for crystal Palace in a lively encounter at home arsenal,
Pierre-Emerick Aubameyang had given the Gunners the lead when Mikel Arteta's team dominated the first half. He was later dismissed for a dangerous duel against Max Meyer.
The Gabonese striker was originally booked by referee Paul Tierney, but VAR upgraded him to a red one.
Otherwise, Richarlison scored the only goal of the game as Everton 1-0 victory BrightonTowards the end of the first half, he curled up in a centimeter shot.
Toffees Dominic Calvert-Lewin later ruled out a goal for VAR's handball.
But the points were shared at Molineux wolves Drawn 1: 1 Newcastle,
Miguel Almiron found the top corner from 15 yards to give the magpies the lead, but Leander Dendoncker brought the hosts back into play with the simplest results from close range.